Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613402 | 1.00 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAKDM4EGAA | |
| SCHEMBL11621125 | 0.88 | LMNA (0.54) | ALDH1A1SMN1; SMN2LMNAKDM4EGAA | |
| SCHEMBL11621562 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAKDM4EGAA | |
| SCHEMBL11617163 | 0.85 | KDM4E (0.39) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL11617162 | 0.85 | KDM4E (0.39) | ALDH1A1SMN1; SMN2LMNAKDM4EPOLB | |
| SCHEMBL11613651 | 0.85 | KDM4E (0.46) | KDM4EPOLBPKMHSD17B10 | |
| SCHEMBL11613646 | 0.85 | KDM4E (0.46) | KDM4EPOLBPKMHSD17B10 | |
| SCHEMBL11615933 | 0.83 | RAB9A (0.43) | ALDH1A1SMN1; SMN2LMNAKDM4EGAA | |
| SCHEMBL11614682 | 0.83 | TSHR (0.54) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL11617070 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |