SCHEMBL11617023

SCHEMBL11617023

CC(c1cc(C(C)(C)CC(C)(C)C)c(O)c(C(C)(C)CC(C)(C)C)c1)c1cc(C(C)(C)CC(C)(C)C)c(O)c(C(C)(C)CC(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.38
CYP2D6 P10635 2/20 0.36
CYP1A2 P05177 2/20 0.36
CA2 P00918 5/20 0.34
CA1 P00915 3/20 0.34
ALDH1A1 P00352 5/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
TYR P14679 1/20 0.33
ALOX15 P16050 4/20 0.32
CYP3A4 P08684 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP2C9 P11712 2/20 0.32
HSD17B10 Q99714 2/20 0.32
IDH1 O75874 1/20 0.32
LMNA P02545 3/20 0.32
TSHR P16473 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10348751 0.84 ALDH1A1 (0.38) SHBGCYP2D6CYP1A2CA2CA1
SCHEMBL5929169 0.81 AKR1C3 (0.37) ALDH1A1SMN1; SMN2CYP3A4HIF1ACYP2C9
SCHEMBL9332354 0.79 SHBG (0.48) SHBGCYP2D6CYP1A2CA2CA1
SCHEMBL11617024 0.79 CNR1 (0.39)
SCHEMBL226090 0.78 ALDH1A1 (0.58) SHBGCYP2D6CYP1A2CA2CA1
SCHEMBL767213 0.78 SHBG (0.52) SHBGCYP2D6CYP1A2CA2CA1
SCHEMBL284652 0.77 CA2 (0.58) CYP2D6CYP1A2CA2CA1ALDH1A1
SCHEMBL8340901 0.76 SHBG (0.41) SHBGCYP2D6CYP1A2CA2CA1
SCHEMBL9511225 0.76 ALDH1A1 (0.41) SHBGCYP2D6CYP1A2CA2CA1
SCHEMBL6395097 0.75 SMN1; SMN2 (0.41) SHBGCYP2D6CA2CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4117178-A PHENOLIC ANTIOXIDANTS FOR NON-POLYMERIC HALOGEN COMPOUNDS DURING IMPREGNATION OF STYRENE POLYMER PARTICLES ARCO POLYMERS, INC. (US) 1978-09-26 US claimed
US-4117178-A PHENOLIC ANTIOXIDANTS FOR NON-POLYMERIC HALOGEN COMPOUNDS DURING IMPREGNATION OF STYRENE POLYMER PARTICLES ARCO POLYMERS, INC. (US) 1978-09-26 US disclosed