SCHEMBL8340901

SCHEMBL8340901

CC(C)(C)CC(C)(C)c1cc(N)cc(C(C)(C)CC(C)(C)C)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.41
CA2 P00918 4/20 0.37
CA1 P00915 2/20 0.37
ALDH1A1 P00352 5/20 0.36
CYP3A4 P08684 4/20 0.36
HIF1A Q16665 4/20 0.36
TSHR P16473 3/20 0.36
LMNA P02545 3/20 0.36
ALOX15 P16050 3/20 0.36
MEN1 O00255 2/20 0.36
CYP1A2 P05177 2/20 0.36
MAPK1 P28482 2/20 0.36
BLM P54132 2/20 0.36
KMT2A Q03164 2/20 0.36
ATM Q13315 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CYP2C9 P11712 2/20 0.36
GMNN O75496 1/20 0.36
GABBR2 O75899 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8334076 0.94 CA2 (0.47) CA2CA1ALDH1A1CYP3A4HIF1A
SCHEMBL11520878 0.89 SHBG (0.34) SHBGCA2CA1ALDH1A1CYP3A4
SCHEMBL9332354 0.83 SHBG (0.48) SHBGCA2CA1ALDH1A1CYP3A4
SCHEMBL226090 0.81 ALDH1A1 (0.58) SHBGCA2CA1ALDH1A1CYP3A4
SCHEMBL8336607 0.81 CA2 (0.38) CA2CA1ALDH1A1CYP3A4HIF1A
SCHEMBL767213 0.81 SHBG (0.52) SHBGCA2CA1ALDH1A1CYP3A4
SCHEMBL9511225 0.79 ALDH1A1 (0.41) SHBGCA2CA1ALDH1A1CYP3A4
SCHEMBL8336744 0.79 CNR2 (0.42) CA2CA1ALDH1A1CYP3A4HIF1A
SCHEMBL8335913 0.78 LMNA (0.36) CA2CA1ALDH1A1CYP3A4HIF1A
SCHEMBL11025169 0.78 ALDH1A1 (0.43) SHBGCA2CA1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
US-4152319-A ALPHA, BETA-UNSATURATED AMIDES HAVING STERICALLY HINDERED PHENOLIC GROUP THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-05-01 US disclosed