Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618317 | 0.81 | POLB (0.49) | POLBKDM4EPKMHSD17B10L3MBTL1 | |
| SCHEMBL11621641 | 0.81 | POLB (0.44) | POLBKDM4EPKMMCL1MAPT | |
| SCHEMBL11619447 | 0.79 | KDM4E (0.46) | POLBKDM4EPKMMAPTALDH1A1 | |
| SCHEMBL11619090 | 0.79 | POLB (0.43) | POLBKDM4EPKMMCL1ALDH1A1 | |
| SCHEMBL11618545 | 0.77 | KDM4E (0.61) | POLBKDM4EPKMHSD17B10MAPT | |
| SCHEMBL11613152 | 0.74 | FABP4 (0.47) | POLBKDM4EPKMMCL1HSD17B10 | |
| SCHEMBL11617679 | 0.74 | PKM (0.49) | POLBKDM4EPKMMCL1MAPT | |
| SCHEMBL11617675 | 0.74 | PKM (0.49) | POLBKDM4EPKMMCL1MAPT | |
| SCHEMBL11617074 | 0.71 | ALDH1A1 (0.47) | POLBKDM4EPKMHSD17B10MAPT | |
| SCHEMBL11615779 | 0.69 | KDM4E (0.45) | POLBKDM4EPKML3MBTL1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |