Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615779 | 0.80 | KDM4E (0.45) | KDM4EPKMPOLBFDPSGLA | |
| SCHEMBL11618545 | 0.80 | KDM4E (0.61) | KDM4EPKMPOLBALDH1A1MAPT | |
| SCHEMBL11617342 | 0.79 | POLB (0.44) | KDM4EPKMPOLBALDH1A1MAPT | |
| SCHEMBL11616083 | 0.76 | POLB (0.43) | KDM4EPKMPOLBMAPT | |
| SCHEMBL11142693 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1MAPTAPEX1TDP1 | |
| SCHEMBL11617679 | 0.74 | PKM (0.49) | KDM4EPKMPOLBALDH1A1MAPT | |
| SCHEMBL11617675 | 0.74 | PKM (0.49) | KDM4EPKMPOLBALDH1A1MAPT | |
| SCHEMBL11621641 | 0.74 | POLB (0.44) | KDM4EPKMPOLBALDH1A1MAPT | |
| SCHEMBL11619090 | 0.72 | POLB (0.43) | KDM4EPKMPOLBALDH1A1 | |
| SCHEMBL11618317 | 0.68 | POLB (0.49) | KDM4EPKMPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | claimed |
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |