Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622720 | 0.82 | HTR7 (0.59) | HTR7CYP1A2PTGS2MAPK1ALDH1A1 | |
| SCHEMBL11620914 | 0.77 | HTR7 (0.57) | HTR7CYP1A2PTGS2MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11622342 | 0.75 | ALDH1A1 (0.50) | TDP1KMT2AMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11619893 | 0.73 | CNR2 (0.36) | TDP1KDM4EALDH1A1MPI | |
| Hydrochloric Acid SCHEMBL11619889 | 0.73 | BCHE (0.39) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11619174 | 0.72 | PTGDR2 (0.60) | PTGDR2KMT2AMEN1MAPK1 | |
| SCHEMBL11618301 | 0.71 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL7093315 | 0.71 | PTGS2 (0.43) | HTR7KMT2AMEN1PTGS2MAPK1 | |
| SCHEMBL24871308 | 0.70 | ALDH1A1 (0.47) | PTGDR2TDP1KMT2AMEN1CYP1A2 | |
| SCHEMBL21281979 | 0.70 | KDM4E (0.39) | HTR7PTGDR2TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4074998-A | USING A SUBSTITUTED PHENOXYALKYLAMINE OR PHENYLTHIOALKYLAMINE | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |