Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSK | P41240 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197031 | 1.00 | CSK (0.45) | CSKCYP3A4SLC7A5NLNMMP13 | |
| SCHEMBL1070085 | 0.87 | CSK (0.33) | CSKCYP3A4SLC7A5NLNCYP1A2 | |
| SCHEMBL1070087 | 0.87 | CSK (0.33) | CSKCYP3A4SLC7A5NLNCYP1A2 | |
| SCHEMBL6957264 | 0.86 | CSK (0.32) | CSKCYP3A4SLC7A5NLN | |
| SCHEMBL14151247 | 0.86 | NLN (0.39) | NLN | |
| SCHEMBL30745117 | 0.86 | CSK (0.32) | CSKCYP3A4SLC7A5NLN | |
| SCHEMBL3835499 | 0.86 | LTA4H (0.33) | CSKCYP3A4SLC7A5NLN | |
| SCHEMBL3835494 | 0.86 | LTA4H (0.33) | CSKCYP3A4SLC7A5NLN | |
| SCHEMBL27913327 | 0.84 | CYP3A4 (0.33) | CSKCYP3A4SLC7A5NLNCYP1A2 | |
| SCHEMBL15292000 | 0.83 | SLC15A1 (0.40) | CYP3A4SLC7A5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099010-A | PHTHALOYL AMINO ACID HYDROXAMIC ACIDS | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4077998-A | Phthaloyl amino acid hydroxamic acids | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-03-07 | — | — | US | disclosed |