Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSK | P41240 | 1/20 | 0.32 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070085 | 0.86 | CSK (0.33) | CSKNLNCYP3A4SLC7A5 | |
| SCHEMBL11620101 | 0.86 | CSK (0.45) | CSKNLNCYP3A4SLC7A5 | |
| SCHEMBL1070087 | 0.86 | CSK (0.33) | CSKNLNCYP3A4SLC7A5 | |
| SCHEMBL4197031 | 0.86 | CSK (0.45) | CSKNLNCYP3A4SLC7A5 | |
| SCHEMBL15292000 | 0.85 | SLC15A1 (0.40) | CYP3A4SLC7A5 | |
| SCHEMBL3835499 | 0.84 | LTA4H (0.33) | CSKNLNCYP3A4SLC7A5 | |
| SCHEMBL14151247 | 0.84 | NLN (0.39) | NLN | |
| SCHEMBL3835494 | 0.84 | LTA4H (0.33) | CSKNLNCYP3A4SLC7A5 | |
| SCHEMBL30745117 | 0.84 | CSK (0.32) | CSKNLNCYP3A4SLC7A5 | |
| SCHEMBL27913327 | 0.83 | CYP3A4 (0.33) | CSKNLNCYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757677-B1 | BENZOCYCLOHEXYLIMIDAZOLETHIONE DERIVATIVES | SYNTEX LLC (US) | 2003-06-18 | — | — | EP | disclosed |
| US-5719280-A | REACTING AMINE SUBSTITUTED BENZOCYCLOALKANE WITH DIALKYLOXYACETALDEHYDE IN PRESENCE OF REDUCING AGENT OR CATALYTIC HYDROGENATION, TREATING WITH THIOCYANIC ACID | SYNTEX (U.S.A.) INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0757677-A1 | BENZOCYCLOALKYLAZOLETHIONE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5538988-A | CARDIOVASCULAR DISORDERS AND DOPAMINE HYDROLASE ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. | 1996-07-23 | — | — | US | disclosed |
| WO-1995029165-A2 | BENZOCYCLOALKYLAZ0LETHIONE DERIVATIVES AS DOPAMIN BETA-HYDROXYLASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1995-11-02 | — | — | WO | disclosed |