Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621616 | 0.89 | ALOX15 (0.51) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| Hydrochloric Acid SCHEMBL11619519 | 0.85 | CYP3A4 (0.49) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL11623140 | 0.82 | ALDH1A1 (0.46) | LMNAGBA1CYP1A2CYP2D6CNR1 | |
| SCHEMBL12757503 | 0.79 | ALDH1A1 (0.47) | CYP1A2CYP2D6SLC6A4CYP3A4TSHR | |
| SCHEMBL2659811 | 0.79 | HDAC1 (0.50) | LMNACYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2659813 | 0.79 | HDAC1 (0.50) | LMNACYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18173134 | 0.77 | LOXL2 (0.54) | HIF1AKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL11620639 | 0.76 | ALOX15 (0.53) | LMNACYP1A2ALOX15CYP3A4TDP1 | |
| SCHEMBL11617446 | 0.76 | ALOX15 (0.53) | LMNACYP1A2ALOX15CYP3A4TDP1 | |
| SCHEMBL11620634 | 0.76 | ALOX15 (0.53) | LMNACYP1A2ALOX15CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4006246-A | ANTIULCER, SECRETOLYTIC, ANTITUSSIVE, STIMULANT | BOEHRINGER INGELHEIM GMBH (DT) | 1977-02-01 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |