Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622267 | 1.00 | ALOX15 (0.47) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11706218 | 1.00 | ALOX15 (0.47) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11621259 | 0.88 | KMT2A (0.50) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11620634 | 0.85 | ALOX15 (0.53) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11620639 | 0.85 | ALOX15 (0.53) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11617446 | 0.85 | ALOX15 (0.53) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11623140 | 0.78 | ALDH1A1 (0.46) | ALOX15KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11620181 | 0.77 | LMNA (0.46) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11621081 | 0.77 | ALOX15 (0.58) | ALOX15KMT2APOLBABL1RIN1 | |
| SCHEMBL11616677 | 0.75 | ALOX15 (0.51) | ALOX15KMT2APOLBMAPTPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4006246-A | ANTIULCER, SECRETOLYTIC, ANTITUSSIVE, STIMULANT | BOEHRINGER INGELHEIM GMBH (DT) | 1977-02-01 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |