SCHEMBL11620781

SCHEMBL11620781

COc1nn(-c2ccccc2)c(=O)o1

nearest known ligand 0.78

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.78
MGLL Q99685 6/20 0.78
ABHD16A O95870 2/20 0.71
LIPC P11150 2/20 0.51
LIPE Q05469 2/20 0.51
LPL P06858 1/20 0.51
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551854 0.91 FAAH (0.74) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL6552566 0.88 MGLL (1.00) FAAHMGLLABHD16A
SCHEMBL6552790 0.87 MGLL (0.74) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL6551376 0.85 MGLL (1.00) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL2235103 0.85 ABHD16A (0.74) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL2233598 0.83 ABHD16A (0.72) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL7578034 0.83 ABHD16A (0.68) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL2233406 0.83 ABHD16A (0.72) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL7046228 0.83 ABHD16A (0.72) FAAHMGLLABHD16ALIPCLIPE
SCHEMBL2233786 0.82 MGLL (0.76) FAAHMGLLABHD16ALIPCLIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US disclosed