Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD16A | O95870 | 2/20 | 0.68 |
| ▸ | MGLL | Q99685 | 7/20 | 0.61 |
| ▸ | FAAH | O00519 | 6/20 | 0.61 |
| ▸ | LPL | P06858 | 1/20 | 0.49 |
| ▸ | LIPC | P11150 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620781 | 0.83 | FAAH (0.78) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6551186 | 0.81 | ABHD16A (0.56) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL2233406 | 0.81 | ABHD16A (0.72) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL7046228 | 0.81 | ABHD16A (0.72) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL2233598 | 0.81 | ABHD16A (0.72) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6551854 | 0.78 | FAAH (0.74) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6551089 | 0.77 | ABHD16A (0.67) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL7044439 | 0.75 | MGLL (0.78) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6552790 | 0.72 | MGLL (0.74) | ABHD16AMGLLFAAHLIPCLIPE | |
| SCHEMBL7043178 | 0.72 | ABHD16A (0.59) | ABHD16AMGLLFAAHLPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | Aventis Pharma Deutschland GmbH (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001066531-A1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-09-13 | — | — | WO | disclosed |