Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758387 | 0.87 | DTYMK (0.44) | DTYMKHCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL16401319 | 0.82 | TSHR (0.54) | DTYMKHCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL28910119 | 0.80 | TSHR (0.46) | DTYMKHCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL8831890 | 0.78 | ALDH1A1 (0.34) | DTYMKHCAR3TSHRALDH1A1TDP1 | |
| SCHEMBL22832208 | 0.78 | MAPT (0.34) | HCAR3ALDH1A1TDP1CYP3A4BACE1 | |
| SCHEMBL3807102 | 0.77 | KMT2A (0.35) | HCAR3TSHRCASP6ALDH1A1TDP1 | |
| SCHEMBL11625787 | 0.76 | RXRA (0.47) | DTYMKHCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL10426613 | 0.76 | FBP1 (0.49) | DTYMKHCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL11650787 | 0.75 | DTYMK (0.44) | DTYMKHCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL7172390 | 0.75 | GPR35 (0.46) | TSHRCASP6ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067995-A | ANTIALLERGENS; N,N-(CYANO-PHENYLENE)-DIOXAMIC ACID DERIVATIVES | THE UPJOHN COMPANY (US) | 1978-01-10 | — | — | US | disclosed |