Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514802 | 0.72 | ALDH1A1 (0.48) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL1162763 | 0.71 | PTGS2 (0.34) | PTGS1PTGS2KDM4EGAASMN1; SMN2 | |
| SCHEMBL6341308 | 0.71 | PTGS1 (0.66) | PTGS1CYP19A1PTGS2 | |
| SCHEMBL18735624 | 0.70 | CYP1A2 (0.36) | PTGS1PTGS2 | |
| SCHEMBL1162420 | 0.70 | PTGS2 (0.46) | PTGS1PTGS2 | |
| SCHEMBL18735628 | 0.68 | CYP11B1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL31349179 | 0.68 | PTGS1 (0.85) | PTGS1CYP19A1PTGS2 | |
| SCHEMBL28321243 | 0.68 | CYP1A1 (0.32) | KDM4E | |
| SCHEMBL6734355 | 0.67 | PTGS1 (0.64) | PTGS1CYP19A1PTGS2 | |
| SCHEMBL6739113 | 0.66 | PTGS1 (0.63) | PTGS1CYP19A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462120-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2012-05-31 | — | — | US | disclosed |
| WO-2011017261-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | PNPO, CYP1B1, PRXL2A | PTGS1 1019/4885CYP19A1 678/4885PTGS2 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.