Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.31 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.31 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162274 | 0.71 | PTGS1 (0.56) | PTGS2PTGS1KDM4EGAASMN1; SMN2 | |
| SCHEMBL1162420 | 0.71 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL17514802 | 0.70 | ALDH1A1 (0.48) | ALDH1A1CTSAMAPTCYP1A1CYP1A2 | |
| SCHEMBL1936061 | 0.69 | KDM4E (0.38) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1937564 | 0.66 | EDNRA (0.43) | PTGS2ALDH1A1 | |
| SCHEMBL13843677 | 0.63 | PGR (0.41) | CASP3SENP7 | |
| SCHEMBL14324533 | 0.63 | L3MBTL1 (0.37) | ALDH1A1CTSAMAPTCYP1A2CYP2C9 | |
| SCHEMBL14323527 | 0.63 | L3MBTL1 (0.37) | ALDH1A1CTSAMAPTCYP1A2CYP2C9 | |
| SCHEMBL2353756 | 0.62 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL1559199 | 0.62 | PDE3B (0.40) | PTGS2AKR1C3AKR1C2CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462120-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2012-05-31 | — | — | US | disclosed |
| WO-2011017261-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | PNPO, CYP1B1, PRXL2A | PTGS2 1491/4885ALDH1A1 744/4885AKR1C3 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.