Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.65 |
| ▸ | CA9 | Q16790 | 5/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | NSD2 | O96028 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248770 | 1.00 | GPR35 (0.65) | GPR35CA9CA12CA1CA2 | |
| SCHEMBL6010796 | 0.86 | GPR35 (0.63) | GPR35CA9CA12CA1CA2 | |
| SCHEMBL8089659 | 0.81 | GPR35 (0.42) | GPR35CA9CA12CA1CA2 | |
| SCHEMBL9310524 | 0.80 | GPR35 (0.69) | GPR35CA9CA12CA1CA2 | |
| SCHEMBL310420 | 0.80 | GPR35 (0.69) | GPR35L3MBTL1ALDH1A1CYP3A4TTR | |
| Niclofolan SCHEMBL29385615 | 0.80 | GPR35 (0.57) | GPR35CA9CA12CA1CA2 | |
| SCHEMBL8903476 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4172077 | 0.80 | TTR (0.67) | GPR35CA9CA12CA1CA2 | |
| SCHEMBL10610184 | 0.80 | ALDH1A1 (0.47) | GPR35ALDH1A1CYP3A4MAPTMEN1 | |
| Niclofolan SCHEMBL1498232 | 0.80 | GPR35 (0.57) | GPR35CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123429-A | 1:1 Chromiferous complex azo compounds having a bidentate chelating group and a monofunctional neutral ligand | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-10-31 | — | — | US | disclosed |