Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517432 | 0.85 | ATM (0.40) | CETPPOLB | |
| SCHEMBL11516078 | 0.82 | OGG1 (0.38) | LMNAPOLBKCNH2 | |
| SCHEMBL11516559 | 0.80 | LMNA (0.36) | LMNA | |
| SCHEMBL11628654 | 0.78 | CETP (0.40) | CETPVNN1SLC22A12LMNAPOLB | |
| SCHEMBL11518124 | 0.74 | CASR (0.36) | — | |
| SCHEMBL3147185 | 0.74 | GPR3 (0.50) | CETPCHRM2CHRM1CHRM3SLC22A12 | |
| SCHEMBL6764359 | 0.73 | KCNH2 (0.44) | CETPCHRM2CHRM1CHRM3SLC22A12 | |
| SCHEMBL5270292 | 0.71 | KCNH2 (0.47) | CETPCHRM2CHRM1CHRM3SLC22A12 | |
| SCHEMBL11746054 | 0.71 | KIF11 (0.39) | CETPCHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL1047410 | 0.69 | CETP (0.46) | CETPHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |