Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878505 | 0.79 | — | — | |
| SCHEMBL4659351 | 0.76 | ALOX5 (0.40) | ALDH1A1KMT2AFAAHCNR2TDP1 | |
| Phenaceturic Acid SCHEMBL196523 | 0.76 | ATM (0.62) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| Phenaceturic Acid SCHEMBL14126285 | 0.76 | ATM (0.62) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL1807771 | 0.75 | TSHR (0.44) | ALDH1A1KMT2AFAAHCNR2TDP1 | |
| SCHEMBL11288698 | 0.73 | ATM (0.59) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL935646 | 0.73 | CA2 (0.61) | ALDH1A1LMNAATM | |
| SCHEMBL5664867 | 0.72 | ALOX5 (0.46) | ALDH1A1ALOX5TSHRSLC1A3SLC1A2 | |
| SCHEMBL11632040 | 0.71 | ALDH1A1 (0.56) | ALDH1A1LMNASHMT1SHMT2KMT2A | |
| SCHEMBL8277220 | 0.71 | ALDH1A1 (0.60) | ALDH1A1LMNASHMT1SHMT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |