Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623725 | 0.87 | CYP3A4 (0.53) | OGAALDH1A1HRH3KMT2ACYP3A4 | |
| SCHEMBL11620917 | 0.83 | OGA (0.46) | OGAALDH1A1HRH3KMT2AMEN1 | |
| SCHEMBL20883809 | 0.82 | KMT2A (0.54) | OGAALDH1A1KMT2ACYP2C9MEN1 | |
| SCHEMBL11624932 | 0.82 | KMT2A (0.48) | ALDH1A1HRH3KMT2ACYP1A2CYP2C9 | |
| SCHEMBL11622595 | 0.82 | KCNK3 (0.51) | ALDH1A1HRH3KMT2ACYP2C9CYP2C19 | |
| SCHEMBL11625127 | 0.82 | KMT2A (0.48) | ALDH1A1HRH3KMT2ACYP1A2MEN1 | |
| SCHEMBL5554008 | 0.81 | SLC6A3 (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL6447344 | 0.81 | SLC6A3 (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL11626554 | 0.78 | TEAD1 (0.51) | ALDH1A1HRH3KMT2ACYP3A4CYP3A5 | |
| SCHEMBL22542160 | 0.78 | KMT2A (0.53) | ALDH1A1KMT2ACYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125612-A | N-1-(p-Biphenylalkyl)piperazines and their use as anti-inflammatory agents | SCHERING CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |