Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624549 | 0.84 | ADH5 (0.64) | ADH5HSD11B1CYP3A4CYP2E1CYP2A6 | |
| SCHEMBL12342913 | 0.80 | CYP3A4 (0.47) | HSD11B1CYP3A4CYP2E1CYP2A6ALDH1A1 | |
| SCHEMBL10903820 | 0.75 | MAPT (0.44) | ADH5CYP3A4CYP2E1CYP2A6ALDH1A1 | |
| SCHEMBL29187775 | 0.71 | LMNA (0.45) | ADH5CYP3A4CYP2E1CYP2A6ALDH1A1 | |
| SCHEMBL15354395 | 0.68 | TNKS2 (0.53) | HSD11B1TNKS2CYP3A4CYP2A6BACE1 | |
| SCHEMBL23903543 | 0.68 | KDR (0.40) | — | |
| SCHEMBL2615986 | 0.67 | CYP2A6 (0.47) | HSD11B1TNKS2CYP2A6ABL1CYP2D6 | |
| SCHEMBL14428964 | 0.67 | CYP3A4 (0.50) | CYP3A4CYP2E1CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL11620333 | 0.67 | ADH5 (0.48) | ADH5CYP3A4CYP2E1CYP2A6ALDH1A1 | |
| SCHEMBL8498623 | 0.66 | CYP3A4 (0.50) | HSD11B1CYP3A4CYP2E1CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117142-A | DISUBSTITUTED TRIPHENYLMETHYLMIDAZOLES FOR TREATING MYCOTIC INFECTIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | claimed |