Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.72 |
| ▸ | QDPR | P09417 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 2/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315662 | 0.88 | PDE4B (0.61) | PDE4BQDPRPDE4APDE4CPDE4D | |
| SCHEMBL11624456 | 0.86 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7743993 | 0.84 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21051331 | 0.82 | ALDH1A1 (0.66) | PDE4B | |
| Hydrochloric Acid SCHEMBL11627075 | 0.79 | SLC6A2 (0.54) | PDE4BQDPRPDE4APDE4CPDE4D | |
| Bicarbonate SCHEMBL9574485 | 0.78 | PDE4B (0.60) | PDE4BQDPRPDE4APDE4CPDE4D | |
| SCHEMBL11625021 | 0.78 | DRD2 (0.53) | PDE4B | |
| SCHEMBL21051478 | 0.77 | QDPR (0.48) | PDE4BQDPR | |
| SCHEMBL21051299 | 0.77 | QDPR (0.48) | PDE4BQDPR | |
| SCHEMBL21051300 | 0.77 | QDPR (0.48) | PDE4BQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072685-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1978-02-07 | — | — | US | disclosed |