Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631007 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KMT2APOLBLMNARAB9A | |
| SCHEMBL11627645 | 0.89 | ALDH1A1 (0.57) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL11627596 | 0.84 | FLT1 (0.52) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11624745 | 0.76 | NLRP3 (0.74) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL11630984 | 0.76 | NLRP3 (0.62) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL11628383 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL11625380 | 0.75 | MEN1 (0.55) | ALDH1A1KMT2ARXFP1SMN1; SMN2LMNA | |
| SCHEMBL11624959 | 0.75 | NLRP3 (0.60) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL11624474 | 0.74 | KDM1A (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL11628817 | 0.74 | NLRP3 (0.48) | ALDH1A1KMT2ALMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066639-A | BENZENE-SULFONYL SEMICARBAZIDES AND PROCESS FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |