Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 10/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 7/20 | 0.59 |
| ▸ | DRD2 | P14416 | 5/20 | 0.59 |
| ▸ | DRD3 | P35462 | 5/20 | 0.59 |
| ▸ | DRD5 | P21918 | 6/20 | 0.58 |
| ▸ | DRD4 | P21917 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236565 | 0.98 | TP53 (0.67) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL5004014 | 0.93 | HRH1 (0.66) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL9162693 | 0.88 | HPGD (0.67) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL11258045 | 0.83 | HTR1A (0.62) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL28360925 | 0.83 | TP53 (0.69) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL10993737 | 0.83 | L3MBTL1 (0.55) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL5145157 | 0.81 | HPGD (0.78) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL11628319 | 0.81 | L3MBTL1 (0.97) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL11631075 | 0.80 | HPGD (0.81) | TP53CYP1A2CYP3A4CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL11628772 | 0.80 | LMNA (0.97) | TP53CYP1A2CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091114-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-05-23 | — | — | US | disclosed |