Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631007 | 0.90 | ALDH1A1 (0.56) | ALDH1A1POLBLMNARAB9AGAA | |
| SCHEMBL11627098 | 0.89 | ALDH1A1 (0.51) | ALDH1A1POLBLMNARAB9AMAPT | |
| SCHEMBL11625380 | 0.85 | MEN1 (0.55) | ALDH1A1LMNARAB9AMAPTCA1 | |
| SCHEMBL9143421 | 0.81 | P4HTM (0.49) | ALDH1A1POLBLMNARAB9AMMP2 | |
| SCHEMBL11662718 | 0.81 | MMP1 (0.58) | ALDH1A1POLBLMNAMMP2MMP9 | |
| SCHEMBL9018110 | 0.80 | ALDH1A1 (0.46) | ALDH1A1POLBLMNARAB9AMMP2 | |
| SCHEMBL11852037 | 0.78 | KMT2A (0.52) | ALDH1A1LMNAMMP2MMP9MMP8 | |
| SCHEMBL11628245 | 0.77 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAGAACA1 | |
| SCHEMBL11629012 | 0.77 | MAPT (0.61) | ALDH1A1POLBLMNARAB9AMAPT | |
| SCHEMBL19508785 | 0.76 | NPC1 (0.57) | ALDH1A1POLBRAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066639-A | BENZENE-SULFONYL SEMICARBAZIDES AND PROCESS FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |