Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | GRK2 | P25098 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627645 | 0.90 | ALDH1A1 (0.57) | ALDH1A1POLBLMNACA12CA1 | |
| SCHEMBL11627098 | 0.90 | ALDH1A1 (0.51) | ALDH1A1POLBLMNAKMT2ARAB9A | |
| SCHEMBL11853703 | 0.82 | FLT1 (0.54) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL11627596 | 0.79 | FLT1 (0.52) | ALDH1A1LMNACA1CA2 | |
| SCHEMBL11624745 | 0.79 | NLRP3 (0.74) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL11630984 | 0.79 | NLRP3 (0.62) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL11625380 | 0.78 | MEN1 (0.55) | ALDH1A1LMNAKMT2ACA12CA1 | |
| SCHEMBL11624959 | 0.78 | NLRP3 (0.60) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL13401887 | 0.76 | HTT (0.68) | ALDH1A1POLBKMT2ACA12CA1 | |
| SCHEMBL11629012 | 0.76 | MAPT (0.61) | ALDH1A1POLBLMNAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066639-A | BENZENE-SULFONYL SEMICARBAZIDES AND PROCESS FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |