Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11632202 | 0.92 | INSR (0.56) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL11633217 | 0.89 | INSR (0.56) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Iodide SCHEMBL11635184 | 0.89 | INSR (0.56) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11633252 | 0.88 | MAPT (0.56) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL11627911 | 0.85 | MAPT (0.54) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11631456 | 0.78 | ADRB2 (0.50) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Iodide SCHEMBL11631709 | 0.74 | ADRB2 (0.50) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL11630617 | 0.74 | ADRB2 (0.50) | INSRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL1049070 | 0.73 | CYP2D6 (0.64) | INSRMAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1713242 | 0.72 | MAPT (0.67) | INSRMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085112-A | 2-Formyl-3-alkyl-benzothiazolium halide oxime | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1978-04-18 | — | — | US | disclosed |