Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555378 | 0.86 | TSHR (0.34) | TSHRGABRA1GABRB2CYP3A4HIF1A | |
| Benzene SCHEMBL27540030 | 0.81 | LMNA (0.43) | TRPA1ALDH1A1ALOX15HSD17B10L3MBTL1 | |
| SCHEMBL1901307 | 0.81 | LMNA (0.43) | TRPA1ALDH1A1ALOX15HSD17B10L3MBTL1 | |
| SCHEMBL1902791 | 0.77 | ALOX15 (0.34) | TSHRTRPA1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8858132 | 0.75 | HDAC4 (0.36) | TSHRTRPA1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11696979 | 0.71 | CHRNA7 (0.34) | TSHRSMN1; SMN2ALDH1A1TP53HSP90AA1 | |
| SCHEMBL11692235 | 0.70 | ACHE (0.37) | ALDH1A1CYP3A4TDP1HTT | |
| SCHEMBL22156385 | 0.69 | TSHR (0.42) | TSHRTRPA1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL5085704 | 0.68 | HRH1 (0.48) | TRPA1CYP3A4TDP1LMNA | |
| SCHEMBL27459336 | 0.67 | ALDH1A1 (0.39) | TSHRALDH1A1TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083834-A | CONJUGATED DIENE POLYMER | JAPAN SYNTHETIC RUBBER CO., LTD. (JA) | 1978-04-11 | — | — | US | claimed |
| US-4083834-A | CONJUGATED DIENE POLYMER | JAPAN SYNTHETIC RUBBER CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |