⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856 | 0.65 | — | — | |
| SCHEMBL3431 | 0.55 | — | — | |
| SCHEMBL146255 | 0.55 | — | — | |
| SCHEMBL15284357 | 0.53 | — | — | |
| SCHEMBL15284394 | 0.53 | — | — | |
| SCHEMBL15284451 | 0.53 | — | — | |
| SCHEMBL2233490 | 0.52 | — | — | |
| SCHEMBL2233947 | 0.52 | — | — | |
| SCHEMBL2233919 | 0.52 | — | — | |
| SCHEMBL2230228 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | claimed |
| US-20050203087-A1 | Inhibitors of protein tyrosine phosphatase 1B | WYETH | 2005-09-15 | — | — | US | claimed |
| US-12024549-B2 | Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof | AJINOMOTO CO., INC. (JP) | 2024-07-02 | — | — | US | disclosed |
| US-20240165260-A1 | CONJUGATES OF ANTIBODY AND FUNCTIONAL SUBSTANCE OR SALTS THEREOF, AND COMPOUNDS USED IN PRODUCTION OF THE SAME OR SALTS THEREOF | AJINOMOTO CO., INC. (JP) | 2024-05-23 | — | — | US | disclosed |
| US-20240115719-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME | AJINOMOTO CO., INC. (JP) | 2024-04-11 | — | — | US | disclosed |
| EP-4349373-A1 | CONJUGATE OF ANTIBODY AND FUNCTIONAL SUBSTANCE OR SALT OF SAID CONJUGATE, AND COMPOUND FOR USE IN PRODUCTION OF SAID CONJUGATE OR SALT OF SAID COMPOUND | AJINOMOTO CO., INC. (JP) | 2024-04-10 | — | — | EP | disclosed |
| EP-4306535-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED USING SAME | AJINOMOTO CO., INC. (JP) | 2024-01-17 | — | — | EP | disclosed |
| US-20240000965-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME | AJINOMOTO CO., INC. (JP) | 2024-01-04 | — | — | US | disclosed |
| US-20240000964-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME | AJINOMOTO CO., INC. (JP) | 2024-01-04 | — | — | US | disclosed |
| WO-2023234416-A1 | AFFINITY SUBSTANCE, COMPOUND, AND ANTIBODY AND THEIR SALTS | 味の素株式会社 | 2023-12-07 | — | — | WO | disclosed |
| EP-4279502-A1 | COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED THEREFROM | AJINOMOTO CO., INC. (JP) | 2023-11-22 | — | — | EP | disclosed |
| US-20040214832-A1 | Piperazine derivative renin inhibitors | WARNER-LAMBERT COMPANY LLC | 2004-10-28 | — | — | US | disclosed |
| WO-2004089903-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |
| WO-2004089915-A1 | PIPERAZINE DERIVATIVE RENIN INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20040204455-A1 | Piperidine derivative rennin inhibitors | WARNER-LAMBERT COMPANY LLC | 2004-10-14 | — | — | US | disclosed |
| US-6583089-B1 | Pre- and postemergence herbicides such as (5,5-dimethyl-1,3-dioxocyclohex-2yl)(6-methoxy-3a,4-dihydro-3H -chromeno(4,3c) isoxazolin-9-yl)methanone, formed by acylation and rearranging in the presence of catalysts | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-24 | — | — | US | disclosed |
| EP-1181295-A2 | TRICYCLIC BENZOYLCYCLOHEXANEDIONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| EP-1163240-A1 | TRICYCLIC BENZOYLPYRAZOLE DERIVATIVES USED AS A HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000073311-A2 | TRICYCLIC BENZOYLCYCLOHEXANEDIONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000055158-A1 | TRICYCLIC BENZOYLPYRAZOLE DERIVATIVES USED AS A HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-21 | — | — | WO | disclosed |