Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626985 | 0.85 | CA2 (0.41) | HTTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL11633568 | 0.82 | KMT2A (0.41) | MAPTHTTKDM4EGAAALDH1A1 | |
| SCHEMBL11631129 | 0.76 | ALDH1A1 (0.41) | MAPTHTTKDM4EGAAALDH1A1 | |
| SCHEMBL11631687 | 0.75 | MAPT (0.41) | MAPTHTTKDM4EGAAALDH1A1 | |
| SCHEMBL11645697 | 0.74 | TAAR1 (0.40) | MAPTHTTKDM4EGAAALDH1A1 | |
| SCHEMBL11643819 | 0.74 | CYP2D6 (0.41) | MAPTHTTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11631704 | 0.70 | KMT2A (0.37) | HTTKMT2ALMNAMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL11631418 | 0.69 | KMT2A (0.37) | MAPTHTTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL28270503 | 0.66 | SOS1 (0.45) | — | |
| SCHEMBL11629598 | 0.66 | ALDH1A1 (0.44) | MAPTHTTKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079137-A | FOR TREATMENT OF VASCULAR AND CARDIAC DISEASES | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1978-03-14 | — | — | US | disclosed |