Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631389 | 0.87 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1DRD2RAD52MAPT | |
| SCHEMBL11629455 | 0.83 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1DRD2SLC6A4MAPT | |
| SCHEMBL11631327 | 0.82 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1DRD2MAPTLMNA | |
| SCHEMBL11631902 | 0.82 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1DRD2MAPTPDE6D | |
| SCHEMBL11633522 | 0.81 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1DRD2TP53MEN1 | |
| SCHEMBL11630384 | 0.81 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1SLC6A4MAPTLMNA | |
| SCHEMBL11632747 | 0.81 | L3MBTL1 (0.47) | L3MBTL1TP53MEN1KMT2A | |
| SCHEMBL11632940 | 0.81 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1DRD2SLC6A4RAD52 | |
| SCHEMBL11631445 | 0.80 | SIGMAR1 (0.47) | L3MBTL1TP53MEN1KMT2A | |
| SCHEMBL11629868 | 0.80 | SIGMAR1 (0.47) | L3MBTL1TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |