Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629904 | 0.91 | L3MBTL1 (0.47) | L3MBTL1CCR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11628957 | 0.90 | L3MBTL1 (0.51) | L3MBTL1CARM1PRMT6ALDH1A1MAPT | |
| SCHEMBL11633834 | 0.88 | CARM1 (0.47) | L3MBTL1CCR3CARM1PRMT6MEN1 | |
| SCHEMBL11632598 | 0.88 | L3MBTL1 (0.49) | L3MBTL1CCR3ALDH1A1MAPTSIGMAR1 | |
| SCHEMBL11629421 | 0.87 | L3MBTL1 (0.48) | L3MBTL1CCR3ALDH1A1MAPTSIGMAR1 | |
| SCHEMBL11635081 | 0.86 | L3MBTL1 (0.56) | L3MBTL1MEN1ALDH1A1LMNAPOLB | |
| SCHEMBL11629077 | 0.86 | L3MBTL1 (0.56) | L3MBTL1MEN1ALDH1A1LMNAPOLB | |
| SCHEMBL11631389 | 0.85 | L3MBTL1 (0.55) | L3MBTL1CARM1PRMT6MEN1ALDH1A1 | |
| SCHEMBL11633867 | 0.84 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL11744576 | 0.83 | L3MBTL1 (0.53) | L3MBTL1CCR3ALDH1A1MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |