Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632747 | 0.98 | L3MBTL1 (0.47) | L3MBTL1SIGMAR1SLC18A3MEN1TP53 | |
| SCHEMBL11629868 | 0.97 | SIGMAR1 (0.47) | L3MBTL1SIGMAR1SLC18A3MEN1TP53 | |
| SCHEMBL11631445 | 0.97 | SIGMAR1 (0.47) | L3MBTL1SIGMAR1SLC18A3MEN1TP53 | |
| SCHEMBL11631389 | 0.94 | L3MBTL1 (0.55) | L3MBTL1SIGMAR1SLC18A3MEN1TP53 | |
| SCHEMBL11631902 | 0.84 | L3MBTL1 (0.49) | L3MBTL1DRD2ALDH1A1PARP1PARP2 | |
| SCHEMBL11631327 | 0.84 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2ADRD2DRD3 | |
| SCHEMBL11635336 | 0.84 | HTR7 (0.58) | L3MBTL1DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL11632940 | 0.83 | L3MBTL1 (0.47) | L3MBTL1SIGMAR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL11632481 | 0.82 | L3MBTL1 (0.49) | L3MBTL1SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL11630627 | 0.82 | HTR7 (0.61) | L3MBTL1DRD2DRD4DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |