Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27413921 | 0.88 | ALDH1A1 (0.51) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL11535859 | 0.83 | LMNA (0.53) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL30731163 | 0.76 | KMT2A (0.58) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL9944382 | 0.76 | KMT2A (0.58) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL14060127 | 0.76 | CES2 (0.53) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL21473833 | 0.75 | TSHR (0.62) | LMNAL3MBTL1KMT2AALDH1A1TDP1 | |
| SCHEMBL11777806 | 0.75 | MEN1 (0.59) | LMNAL3MBTL1KMT2AALDH1A1NPC1 | |
| SCHEMBL8462360 | 0.75 | TSHR (0.62) | LMNAL3MBTL1KMT2AALDH1A1TDP1 | |
| SCHEMBL11632540 | 0.75 | MEN1 (0.49) | L3MBTL1NAPRTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29179770 | 0.75 | ALDH1A1 (0.51) | LMNAL3MBTL1NAPRTP4HTMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085277-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-18 | — | — | US | disclosed |
| US-4001225-A | Pyridyl substituted 7-αesters of 3 heterothio 7-acetamido cephalosporanic acids | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-01-04 | — | — | US | disclosed |
| US-4000133-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-12-28 | — | — | US | disclosed |