Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18129456 | 0.86 | KEAP1 (0.57) | L3MBTL1MAPTALDH1A1LMNACHEK1 | |
| SCHEMBL11635209 | 0.81 | CHEK1 (0.55) | L3MBTL1MAPTALDH1A1LMNACHEK1 | |
| SCHEMBL69132 | 0.77 | ALDH1A1 (0.88) | L3MBTL1MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL581124 | 0.75 | ALDH1A1 (1.00) | L3MBTL1MAPTALDH1A1LMNAMEN1 | |
| Anthraquinone SCHEMBL8941397 | 0.75 | ALDH1A1 (1.00) | L3MBTL1MAPTALDH1A1LMNAUSP2 | |
| SCHEMBL461660 | 0.75 | ALDH1A1 (1.00) | L3MBTL1MAPTALDH1A1LMNAUSP2 | |
| SCHEMBL20256467 | 0.75 | ADORA2A (0.56) | L3MBTL1MAPTALDH1A1CHEK1TDP1 | |
| SCHEMBL28230943 | 0.75 | GPR3 (0.52) | L3MBTL1MAPTALDH1A1CHEK1GPR3 | |
| SCHEMBL28450076 | 0.74 | GPR3 (0.47) | L3MBTL1ALDH1A1CHEK1GPR3MEN1 | |
| SCHEMBL31472931 | 0.74 | GPR3 (0.75) | L3MBTL1ALDH1A1CHEK1GPR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103015-A | TRICYCLIC THIOXANTHONE-10,10-DIOXIDES | BURROUGHS WELLCOME CO. (US) | 1978-07-25 | — | — | US | disclosed |