Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CD40 | P25942 | 1/20 | 0.39 |
| ▸ | CD40LG | P29965 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635735 | 1.00 | APEX1 (0.44) | APEX1L3MBTL1ALDH1A1CYP2C9KCNMA1 | |
| SCHEMBL11636816 | 0.87 | TIMP3 (0.47) | L3MBTL1ALDH1A1KCNMA1CYP1A2DDX3X | |
| SCHEMBL11601945 | 0.84 | ALDH1A1 (0.52) | APEX1ALDH1A1CYP1A2KMT2AUSP2 | |
| SCHEMBL11634224 | 0.84 | APEX1 (0.48) | APEX1ALDH1A1CYP1A2KMT2AUSP2 | |
| SCHEMBL11632695 | 0.83 | APEX1 (0.47) | APEX1ALDH1A1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL11633417 | 0.82 | ALDH1A1 (0.41) | APEX1L3MBTL1ALDH1A1CYP2C9KCNMA1 | |
| SCHEMBL11512365 | 0.81 | KCNMA1 (0.46) | APEX1ALDH1A1KCNMA1CYP1A2CYP3A4 | |
| SCHEMBL11514490 | 0.81 | KCNMA1 (0.43) | APEX1ALDH1A1KCNMA1CYP1A2CYP3A4 | |
| SCHEMBL11442053 | 0.80 | APEX1 (0.44) | APEX1ALDH1A1KCNMA1CYP3A4KMT2A | |
| SCHEMBL11440007 | 0.80 | APEX1 (0.44) | APEX1ALDH1A1CYP2C9KCNMA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |