Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 11/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 11/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 11/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 11/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633834 | 0.89 | CARM1 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3L3MBTL1 | |
| SCHEMBL11632598 | 0.89 | L3MBTL1 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3L3MBTL1 | |
| SCHEMBL11629421 | 0.86 | L3MBTL1 (0.48) | CHRNB2CHRNA4CHRNB4CHRNA3L3MBTL1 | |
| SCHEMBL11633867 | 0.84 | L3MBTL1 (0.54) | L3MBTL1GRIN1GRIN2BSIGMAR1KDM4E | |
| SCHEMBL11628957 | 0.83 | L3MBTL1 (0.51) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11744576 | 0.83 | L3MBTL1 (0.53) | L3MBTL1GRIN1GRIN2BSIGMAR1KDM4E | |
| SCHEMBL11632481 | 0.82 | L3MBTL1 (0.49) | L3MBTL1SIGMAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11629077 | 0.82 | L3MBTL1 (0.56) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11630402 | 0.80 | L3MBTL1 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3L3MBTL1 | |
| SCHEMBL11634062 | 0.80 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |