Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632598 | 0.97 | L3MBTL1 (0.49) | L3MBTL1CCR3SIGMAR1HRH3DRD4 | |
| SCHEMBL11628957 | 0.93 | L3MBTL1 (0.51) | L3MBTL1DRD4ACHEKDM4EALDH1A1 | |
| SCHEMBL11744576 | 0.89 | L3MBTL1 (0.53) | L3MBTL1CCR3SIGMAR1DRD4KDM4E | |
| SCHEMBL11633867 | 0.88 | L3MBTL1 (0.54) | L3MBTL1SIGMAR1DRD4KDM4EALDH1A1 | |
| SCHEMBL11634062 | 0.87 | L3MBTL1 (0.43) | L3MBTL1HRH3ACHEALDH1A1GAA | |
| SCHEMBL11630384 | 0.87 | L3MBTL1 (0.53) | L3MBTL1CCR3SIGMAR1DRD4ALDH1A1 | |
| SCHEMBL11633880 | 0.86 | CHRNB2 (0.46) | L3MBTL1SIGMAR1KDM4EALDH1A1GAA | |
| SCHEMBL11629077 | 0.86 | L3MBTL1 (0.56) | L3MBTL1DRD4KDM4EALDH1A1GAA | |
| SCHEMBL11634699 | 0.85 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11631967 | 0.83 | L3MBTL1 (0.48) | L3MBTL1SIGMAR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |