Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633880 | 0.89 | CHRNB2 (0.46) | L3MBTL1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL11630384 | 0.88 | L3MBTL1 (0.53) | CARM1PRMT6L3MBTL1CCR3ALDH1A1 | |
| SCHEMBL11630402 | 0.87 | L3MBTL1 (0.44) | CARM1PRMT6L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL11632481 | 0.85 | L3MBTL1 (0.49) | L3MBTL1HTR2AALDH1A1MAPTLMNA | |
| SCHEMBL11635081 | 0.81 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MAPTMEN1LMNA | |
| SCHEMBL11629077 | 0.81 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MAPTMEN1LMNA | |
| SCHEMBL11628957 | 0.80 | L3MBTL1 (0.51) | CARM1PRMT6L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11629904 | 0.80 | L3MBTL1 (0.47) | L3MBTL1CCR3ALDH1A1MAPTLMNA | |
| SCHEMBL11813385 | 0.79 | KDM4E (0.51) | CARM1PRMT6HTR2AALDH1A1MAPT | |
| SCHEMBL11633867 | 0.79 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |