Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636711 | 0.82 | CTSL (0.53) | TACR1MAPTTP53CTSLCTSK | |
| SCHEMBL30873796 | 0.82 | CTSL (0.53) | TACR1MAPTTP53CTSLCTSK | |
| SCHEMBL11636318 | 0.80 | CTSK (0.46) | CTSKCTSSSMN1; SMN2 | |
| SCHEMBL11638523 | 0.79 | CTSK (0.43) | TACR1CTSKCTSSSMN1; SMN2 | |
| SCHEMBL11638583 | 0.79 | CTSK (0.60) | CTSKCTSSSMN1; SMN2POLB | |
| SCHEMBL11638585 | 0.79 | CTSK (0.60) | CTSKCTSSSMN1; SMN2POLB | |
| SCHEMBL28224619 | 0.77 | GPR84 (0.50) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL11636897 | 0.76 | CTSK (0.45) | MAPTCTSKCTSSSMN1; SMN2MEN1 | |
| SCHEMBL27725523 | 0.76 | MAPT (0.44) | TACR1MAPTTP53CTSLCTSK | |
| SCHEMBL5209782 | 0.75 | SSTR3 (0.53) | TACR1MAPTTP53CTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108854-A | Process for preparing substituted glycines | SMITHKLINE CORPORATION (US) | 1978-08-22 | — | — | US | disclosed |
| US-3997584-A | Substituted glycines and intermediates thereof | SMITHKLINE CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3994954-A | Process for preparing substituted glycines | SMITHKLINE CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |