Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972858 | 1.00 | FAAH (0.54) | FAAHCES1EPHX1PPARAEPHX2 | |
| SCHEMBL12330947 | 0.87 | ALDH1A1 (0.52) | EPHX1PPARAEPHX2ACACBLTA4H | |
| SCHEMBL934358 | 0.86 | FAAH (0.51) | FAAHCES1EPHX1PPARAEPHX2 | |
| SCHEMBL933618 | 0.84 | EPHX1 (0.51) | FAAHCES1EPHX1PPARAEPHX2 | |
| SCHEMBL3872336 | 0.82 | HDAC1 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11637942 | 0.81 | ALOX5 (0.59) | — | |
| SCHEMBL9235000 | 0.81 | ALOX5 (0.59) | — | |
| SCHEMBL8003026 | 0.81 | ALOX5 (0.59) | — | |
| SCHEMBL4046194 | 0.81 | FFAR1 (0.56) | FAAHCES1FFAR1FFAR4 | |
| SCHEMBL24264814 | 0.80 | HDAC3 (0.55) | PPARAEPHX2LTA4HHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125541-A | Aryl substituted ketones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125714-A | Aryl substituted cycloalkanones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |