Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11164226 | 0.90 | POLB (0.51) | LMNAPOLB | |
| SCHEMBL11165951 | 0.85 | NR1I2 (0.58) | LMNAPTGIRNR1I2EGFRADRA2A | |
| SCHEMBL11635741 | 0.85 | NR1I2 (0.49) | LMNAPTGIRPTGER4NR1I2EGFR | |
| SCHEMBL11867757 | 0.81 | PTGER4 (0.43) | PTGER4 | |
| SCHEMBL11468014 | 0.79 | LMNA (0.56) | LMNANR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11857025 | 0.79 | PDE4A (0.41) | PTGER4PDE4D | |
| SCHEMBL31448372 | 0.78 | CFTR (0.52) | ADORA3POLB | |
| SCHEMBL11865220 | 0.77 | PDE4D (0.41) | LMNANR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11863918 | 0.77 | GRIN1 (0.46) | LMNAPTGER4PDE4DPOLB | |
| SCHEMBL11867581 | 0.77 | ADORA2A (0.43) | LMNAADORA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |