Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867743 | 0.82 | TSHR (0.39) | PTGER4GRM2BRD4BAZ2ATSHR | |
| SCHEMBL11635900 | 0.81 | LMNA (0.55) | PTGER4 | |
| SCHEMBL11866166 | 0.81 | ALDH1A1 (0.46) | PTGER4DHFRKDM4EALDH1A1NPSR1 | |
| SCHEMBL11858747 | 0.81 | ALDH1A1 (0.46) | PTGER4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11863779 | 0.81 | GSK3B (0.41) | PTGER4KDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL11164226 | 0.80 | POLB (0.51) | — | |
| SCHEMBL14374217 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1NPSR1HSD17B10ABCC1 | |
| SCHEMBL11857025 | 0.77 | PDE4A (0.41) | PTGER4BRD4DHFRKDM4EALDH1A1 | |
| SCHEMBL11857087 | 0.77 | MAPT (0.44) | — | |
| SCHEMBL14347335 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1NPSR1HSD17B10ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |