Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148014 | 0.85 | KMT2A (0.47) | KMT2AKDM4EGLASTAT3ALDH1A1 | |
| SCHEMBL11192940 | 0.81 | KMT2A (0.47) | KMT2AKDM4EGLASTAT3ALDH1A1 | |
| SCHEMBL29035968 | 0.81 | KDM4E (0.52) | KMT2AKDM4EGLASTAT3ALDH1A1 | |
| SCHEMBL29696630 | 0.79 | HTR6 (0.55) | KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17111036 | 0.79 | HTR6 (0.55) | KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL29035976 | 0.79 | RAB9A (0.61) | KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL14564434 | 0.78 | KDM4E (0.47) | KMT2AKDM4EALDH1A1TBXAS1MAPT | |
| SCHEMBL4886606 | 0.77 | MEN1 (0.49) | KMT2AALDH1A1NR3C1PGRNR3C2 | |
| SCHEMBL1598786 | 0.77 | KMT2A (1.00) | KMT2AKDM4E | |
| SCHEMBL2851614 | 0.77 | NR3C1 (0.50) | KMT2AALDH1A1NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232070-A | Quinolinone alkaloid derivative containing acylhydrazone group on 1-site nitrogen atom and preparation method and application thereof | 太原理工大学 | 2022-10-25 | — | — | CN | claimed |
| CN-103524410-A | 4-quinolone-N-acetic acid molecular crystal and preparation method and application thereof | ZHONGSHAN POLYTECHNIC | 2014-01-22 | — | — | CN | disclosed |
| US-4119775-A | ANTIBACTERIAL | RICHARDSON-MERRELL INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-3989687-A | ANTIBACTERIAL | RICHARDSON-MERRELL INC. (US) | 1976-11-02 | — | — | US | disclosed |