Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28213821 | 0.80 | GSK3A (0.32) | GSK3B | |
| SCHEMBL28425134 | 0.77 | USP2 (0.36) | MAOAMAOBUSP2LMNAMAPK1 | |
| SCHEMBL18973130 | 0.77 | P4HB (0.38) | MAOAMAOBMAPT | |
| SCHEMBL18973128 | 0.77 | MAOA (0.45) | MAOAMAOBMAPK1MAPTALDH1A1 | |
| Ethane SCHEMBL28166108 | 0.76 | — | — | |
| SCHEMBL18972985 | 0.73 | MAOA (0.39) | MAOAMAOBMAPK1MAPTALDH1A1 | |
| SCHEMBL18972988 | 0.73 | STK10 (0.35) | — | |
| SCHEMBL28390408 | 0.73 | TSHR (0.46) | USP2LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL7919414 | 0.72 | USP2 (0.43) | MAOAMAOBUSP2LMNAMAPK1 | |
| SCHEMBL28256298 | 0.71 | GSK3A (0.32) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933142-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2021-03-02 | — | — | US | disclosed |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2021-03-02 | — | — | US | disclosed |
| US-20200108150-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL BUSINESS LTD (GB) | 2020-04-09 | — | — | US | disclosed |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2020-02-04 | — | — | US | disclosed |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2020-02-04 | — | — | US | disclosed |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| US-10174094-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2019-01-08 | — | — | US | disclosed |
| US-10174094-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2019-01-08 | — | — | US | disclosed |
| US-20160176942-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS PLC (GB) | 2016-06-23 | — | — | US | disclosed |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190579-A1 | Functionalisation of Solid Substrates | UCL BUSINESS PLC (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190579-A1 | Functionalisation of Solid Substrates | UCL BUSINESS PLC (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2012-07-26 | — | — | US | disclosed |
| EP-2464972-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL Business PLC (GB) | 2012-06-20 | — | — | EP | disclosed |
| EP-2464974-A1 | FUNCTIONALISATION OF SOLID SUBSTRATES | UCL Business PLC (GB) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011018611-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011018611-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011018613-A1 | FUNCTIONALISATION OF SOLID SUBSTRATES | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011018613-A1 | FUNCTIONALISATION OF SOLID SUBSTRATES | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174094-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | MAOA 194/4885MAOB 242/4885USP2 2243/4885 |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | MAOA 194/4885MAOB 242/4885USP2 2243/4885 |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | MAOA 194/4885MAOB 242/4885USP2 2243/4885 |
| US-20120190579-A1 | Functionalisation of Solid Substrates | XDH, SPR, DAO | MAOA 170/4885MAOB 517/4885USP2 3068/4885 |
| US-20160176942-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | MAOA 194/4885MAOB 242/4885USP2 2243/4885 |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | MAOA 194/4885MAOB 242/4885USP2 2243/4885 |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | MAOA 194/4885MAOB 242/4885USP2 2243/4885 |
| US-20200108150-A1 | REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES | F12, F13A1, F2 | MAOA 193/4885MAOB 213/4885USP2 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.