Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133007 | 0.84 | NNMT (0.42) | NNMTAOC3KDM4ELRRK2HCAR3 | |
| SCHEMBL11637320 | 0.82 | NNMT (0.53) | NNMTKDM4ELRRK2GSK3BALDH1A1 | |
| SCHEMBL6471080 | 0.82 | NNMT (0.41) | NNMTAOC3ADRA2AHCAR3TRPV1 | |
| SCHEMBL5150474 | 0.80 | NNMT (0.41) | NNMTAOC3KDM4ELRRK2HCAR3 | |
| SCHEMBL11637312 | 0.78 | HCAR3 (0.46) | NNMTAOC3KDM4EHCAR3ALDH1A1 | |
| SCHEMBL5133216 | 0.76 | NNMT (0.41) | NNMTAOC3KDM4EHCAR3ALDH1A1 | |
| SCHEMBL3174330 | 0.74 | NNMT (0.67) | NNMTGSK3BALDH1A1MAPTKMT2A | |
| SCHEMBL11637418 | 0.74 | NNMT (0.49) | NNMTLRRK2GSK3BKMT2APIM1 | |
| SCHEMBL30482977 | 0.72 | SIRT6 (0.46) | AOC3KDM4EHCAR3TRPV1GSK3B | |
| SCHEMBL6260914 | 0.72 | NNMT (0.41) | NNMTAOC3KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104385-A | Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates | STERLING DRUG INC. (US) | 1978-08-01 | — | — | US | disclosed |