Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636680 | 0.82 | NNMT (0.47) | NNMTLRRK2KMT2AALDH1A1KDM4E | |
| SCHEMBL8139286 | 0.82 | NPC1 (0.41) | NNMTNPC1RAB9AUSP2TP53 | |
| SCHEMBL11508947 | 0.82 | NPC1 (0.46) | NNMTNPC1RAB9AUSP2TP53 | |
| SCHEMBL16571761 | 0.80 | NPC1 (0.40) | NNMTNPC1RAB9AUSP2TP53 | |
| SCHEMBL3174330 | 0.80 | NNMT (0.67) | NNMTSMN1; SMN2KMT2AALDH1A1PIM1 | |
| SCHEMBL11637418 | 0.79 | NNMT (0.49) | NNMTLRRK2KMT2APIM1GSK3B | |
| SCHEMBL11637312 | 0.77 | HCAR3 (0.46) | NNMTTP53ALDH1A1KDM4EGAA | |
| SCHEMBL4278637 | 0.75 | NPC1 (0.58) | NPC1RAB9AUSP2TP53PKM | |
| SCHEMBL6471080 | 0.74 | NNMT (0.41) | NNMTNPC1RAB9AKMT2ALMNA | |
| SCHEMBL2469953 | 0.72 | NNMT (0.59) | NNMTLRRK2KMT2AHTTPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104385-A | Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates | STERLING DRUG INC. (US) | 1978-08-01 | — | — | US | disclosed |