Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 12/20 | 0.63 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.63 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142328 | 0.85 | NPC1 (0.67) | GPR27AVPR2BCAT2MEN1KMT2A | |
| SCHEMBL6600762 | 0.78 | LMNA (0.46) | GPR27AVPR2MEN1KMT2ANPC1 | |
| SCHEMBL1259483 | 0.78 | LMNA (0.59) | NPC1RAB9AALDH1A1 | |
| SCHEMBL882734 | 0.78 | KMT2A (0.80) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL12726113 | 0.77 | CYP1A2 (0.63) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL12468557 | 0.77 | AVPR2 (0.75) | GPR27AVPR2MEN1KMT2ANPC1 | |
| SCHEMBL1258906 | 0.76 | USP28 (0.83) | — | |
| SCHEMBL18387929 | 0.75 | SMN1; SMN2 (0.78) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL16127847 | 0.74 | ALDH1A1 (0.65) | BCAT2MEN1KMT2AALDH1A1 | |
| SCHEMBL1259363 | 0.73 | LMNA (0.49) | GPR27AVPR2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4102924-A | REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |