SCHEMBL14958645

SCHEMBL14958645

CCCCCCCCCCCCn1c(C)ccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 5/20 0.45
PRKCI P41743 1/20 0.44
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
HTT P42858 4/20 0.44
GALR3 O60755 2/20 0.44
POLB P06746 2/20 0.44
ATM Q13315 2/20 0.44
MAPK1 P28482 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HSP90AA1 P07900 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
RAD52 P43351 1/20 0.44
PAX8 Q06710 1/20 0.44
NR2F2 P24468 1/20 0.44
APOBEC3A P31941 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20139100 1.00 TLR8 (0.45) TLR8PRKCINPC1RAB9AHTT
SCHEMBL14958647 1.00 TLR8 (0.45) TLR8PRKCINPC1RAB9AHTT
SCHEMBL23751998 1.00 TLR8 (0.45) TLR8PRKCINPC1RAB9AHTT
SCHEMBL3141353 0.98 TLR8 (0.46) TLR8PRKCINPC1RAB9AHTT
SCHEMBL4883169 0.90 TSHR (0.50) TLR8PRKCIPOLBNPSR1LMNA
SCHEMBL11339139 0.90 PRKCI (0.50) TLR8PRKCIPOLBNPSR1LMNA
SCHEMBL31469892 0.88 MGLL (0.53) TLR8LMNAKDM4EPTGS1MGLL
SCHEMBL14243368 0.86 TLR8 (0.46) TLR8NPC1RAB9AHTTGALR3
SCHEMBL16405004 0.84 GPR84 (0.39) TLR8NPC1RAB9AHTTGALR3
SCHEMBL7215402 0.81 TLR8 (0.40) TLR8PRKCINPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025027538-A1 PROCESS FOR PREPARING STABLE AND HOMOGENEOUS DISPERSIONS OF SP2 CARBON ALLOTROPES IN LIPOPHILIC MATRIXES AND RELATED COMPOSITE MATERIALS OBTAINABLE THEREFROM ENI S.P.A. (IT) 2025-02-06 WO disclosed
CN-112074503-B Adducts between pyrrole compounds and inorganic oxide hydroxides, superadders, elastomeric compositions comprising superadders and process for their preparation 倍耐力轮胎股份公司 2024-05-14 CN disclosed
CN-110139851-B Adducts formed from primary amines, dicarbonyl derivatives, inorganic oxide hydroxides and SP 2-hybridized carbon allotropes 倍耐力轮胎股份公司 2023-03-21 CN disclosed
US-11414383-B2 Adducts formed from primary amines, dicarbonyl derivatives, inorganic oxide hydroxydes and sp2-hybridized carbon allotropes PIRELLI TYRE S.P.A. (IT) 2022-08-16 US disclosed
EP-3755687-B1 ADDUCT BETWEEN A PYRROLIC COMPOUND AND AN INORGANIC OXIDE HYDROXIDE, A SUPER-ADDUCT BETWEEN A PYRROLIC COMPOUND, AN INORGANIC OXIDE HYDROXIDE AND A CARBON ALLOTROPE, ELASTOMERIC COMPOSITION COMPRISING THE SUPER-ADDUCT AND METHODS FOR PRODUCING THE SAME PIRELLI (IT) 2022-06-29 EP disclosed
EP-3755687-A1 ADDUCT BETWEEN A PYRROLIC COMPOUND AND AN INORGANIC OXIDE HYDROXIDE, A SUPER-ADDUCT BETWEEN A PYRROLIC COMPOUND, AN INORGANIC OXIDE HYDROXIDE AND A CARBON ALLOTROPE, ELASTOMERIC COMPOSITION COMPRISING THE SUPER-ADDUCT AND METHODS FOR PRODUCING THE SAME Pirelli Tyre S.p.A. (IT) 2020-12-30 EP disclosed
CN-112074503-A Adducts between pyrrole compounds and inorganic oxide hydroxides, superaddites between pyrrole compounds, inorganic oxide hydroxides and carbon allotropes, elastomeric compositions comprising said superaddites and process for preparing them 倍耐力轮胎股份公司 2020-12-11 CN disclosed
WO-2019162873-A1 ADDUCT BETWEEN A PYRROLIC COMPOUND AND AN INORGANIC OXIDE HYDROXIDE, A SUPER-ADDUCT BETWEEN A PYRROLIC COMPOUND, AN INORGANIC OXIDE HYDROXIDE AND A CARBON ALLOTROPE, ELASTOMERIC COMPOSITION COMPRISING THE SUPER-ADDUCT AND METHODS FOR PRODUCING THE SAME PIRELLI TYRE S.P.A. (IT) 2019-08-29 WO disclosed
EP-2061825-B1 UNIVERSAL GRIGNARD METATHESIS POLYMERIZATION UNIV CARNEGIE MELLON (US) 2013-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11414383-B2 Adducts formed from primary amines, dicarbonyl derivatives, inorganic oxide hydroxydes and sp2-hybridized carbon allotropes DRD4, DRD2, DAXX TLR8 3866/4885PRKCI 4218/4885NPC1 3410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.