Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637081 | 0.81 | CSNK2A2 (0.60) | MAPTKDM4ETP53HSD17B10SMN1; SMN2 | |
| SCHEMBL11640026 | 0.80 | ACHE (0.50) | ACHEPOLBMAPTKDM4ECYP1A2 | |
| SCHEMBL9798421 | 0.78 | DYRK1A (0.42) | MAPTKDM4ETP53LMNAALDH1A1 | |
| SCHEMBL11633450 | 0.76 | ACHE (0.50) | ACHEPOLBMAPTKDM4ECYP1A2 | |
| SCHEMBL11637174 | 0.75 | GABRP (0.66) | MAPTTP53SMN1; SMN2LMNAALOX15 | |
| SCHEMBL11633630 | 0.75 | TNKS (0.57) | MAPTKDM4ETP53SMN1; SMN2LMNA | |
| SCHEMBL11637749 | 0.75 | KDM4E (0.65) | POLBMAPTKDM4ECYP1A2TP53 | |
| SCHEMBL11634284 | 0.74 | GABRP (0.50) | POLBMAPTKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL11636746 | 0.73 | ALDH1A1 (0.62) | POLBMAPTKDM4ECYP1A2TP53 | |
| SCHEMBL11639561 | 0.73 | PTPRS (0.48) | MAPTKDM4ETP53HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122200-A | 6',2-(2'Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-10-24 | — | — | US | disclosed |
| US-4097582-A | 6',2-(2'-Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-06-27 | — | — | US | disclosed |