Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089480 | 0.86 | BCHE (0.60) | BCHELMNABACE1SLC6A11ANPEP | |
| SCHEMBL7095555 | 0.86 | BCHE (0.60) | BCHELMNABACE1SLC6A11ANPEP | |
| SCHEMBL18067594 | 0.85 | DNM1 (0.53) | BCHELMNAANPEPALDH1A1KDM4E | |
| SCHEMBL14015728 | 0.82 | BCHE (0.57) | BCHELMNABACE1SLC6A11ALDH1A1 | |
| SCHEMBL7278068 | 0.81 | LMNA (0.77) | BCHELMNAKDM4EL3MBTL1MEN1 | |
| SCHEMBL2289990 | 0.81 | LMNA (0.77) | BCHELMNAKDM4EL3MBTL1MEN1 | |
| SCHEMBL1849603 | 0.81 | LMNA (0.77) | BCHELMNAKDM4EL3MBTL1MEN1 | |
| SCHEMBL4403903 | 0.79 | ALDH1A1 (0.57) | BCHELMNABACE1SLC6A11ANPEP | |
| SCHEMBL11100850 | 0.79 | BCHE (0.54) | BCHELMNABACE1SLC6A11ANPEP | |
| SCHEMBL31335199 | 0.79 | ALDH1A1 (0.57) | BCHELMNABACE1SLC6A11ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113972-A | ANTIDEPRESSANTS | BEECHAM GROUP LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |
| US-4101676-A | Diphenylpropylamines to treat depression | BEECHAM GROUP LIMITED (GB) | 1978-07-18 | — | — | US | disclosed |